Synonyms: 1010001D01Rik,Dudlin 2,Dudlin2,Dudulin 2,Dudulin-2,Dudulin2,h pH yde,hTSAP6,Metalloreductase STEAP3,MGC93147, pH yde,Six transmembrane epithelial antigen of prostate 3,Six transmembrane prostate protein 3,Six-transmembrane epithelial antigen of prostate 3,STEA 3,STEA3,STEAP 3,STEAP family member 3,STEAP family member 3 metalloreductase,STEAP3,STMP 3,STMP3,TSAP 6,TSAP6,Tumor suppressor activated pathway protein 6,Tumor suppressor pH yde,Tumor suppressor-activated pathway protein 6
Background: This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants.