Filamin A antibody (Filamin A, alpha)

Details for Product anti-FLNA Antibody No. ABIN6566697
Antigen
Reactivity
Human, Mouse (Murine)
192
129
116
6
3
1
1
Host
Rabbit
172
19
1
Clonality
Polyclonal
Conjugate
This Filamin A antibody is un-conjugated
12
9
9
9
9
9
9
7
7
4
4
4
4
4
2
2
2
Application
Western Blotting (WB)
86
69
59
53
38
15
13
11
7
2
2
2
1
1
Options
Immunogen A synthetic peptide of human FLNA
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name FLNA (FLNA Antibody Abstract)
Background

Synonyms: ABP 280,ABP-280,Actin-binding protein 280,Alpha filamin,Alpha-filamin,APBX,CSBS,CVD1,Endothelial actin binding protein,Endothelial actin-binding protein,Filamin 1,Filamin A alpha,Filamin A,Filamin-1,Filamin-A,FLN,FLN-A,FLN1,FLNA,FLNA,FMD,MNS,NHBP,Non muscle filamin,Non-muscle filamin,OPD,OPD1,OPD2,XLVD,XMVD

Background: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 300kDa

Calculated_MW: 280kDa

Gene ID 2316
UniProt P21333
Pathways TCR Signaling, Maintenance of Protein Location
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Filamin A, alpha (FLNA) antibody (ABIN6566697) Western blot analysis of extracts of various cell lines, using FLNA antibody.