NeuN antibody (RNA Binding Protein, Fox-1 Homolog (C. Elegans) 3)

Details for Product anti-RBFOX3 Antibody No. ABIN6566704
Antigen
  • FOX-3
  • FOX3
  • HRNBP3
  • NEUN
  • Fox-3
  • Hrnbp3
  • NeuN
  • Neuna60
  • Neun
  • RGD1560070
  • RNA binding fox-1 homolog 3
  • RNA binding protein, fox-1 homolog (C. elegans) 3
  • RNA binding protein, fox-1 homolog 3
  • RBFOX3
  • Rbfox3
Reactivity
Human, Mouse (Murine), Rat (Rattus)
83
75
57
5
4
2
2
1
1
1
Host
Rabbit
70
18
3
Clonality
Polyclonal
Conjugate
This NeuN antibody is un-conjugated
8
5
4
4
4
4
4
4
2
2
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
46
40
20
14
13
12
12
7
5
3
2
1
1
Options
Immunogen A synthetic peptide of human RBFOX3
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name RBFOX3 (RBFOX3 Antibody Abstract)
Background

Synonyms: FLJ56884,FLJ58356,Fox-1 homolog C,fox1 homolog C,Fox3,FOX3NeuN,hexaribonucleotide binding protein 3,HRNBP3,NEUN,neuronal nuclei,Rbfox3,RFOX3,RNA binding protein fox-1 homolog 3,RNA binding protein,fox 1 homolog (C. elegans) 3

Background: This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Molecular Weight

Observed_MW: 34kDa

Calculated_MW: 33kDa/35kDa

Gene ID 146713
UniProt A6NFN3
Application Notes WB 1:500 - 1:2000 IF 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-RNA Binding Protein, Fox-1 Homolog (C. Elegans) 3 (RBFOX3) antibody (ABIN6566704) Immunofluorescence analysis of MCF-7 cells using RBFOX3 antibody.
Image no. 2 for anti-RNA Binding Protein, Fox-1 Homolog (C. Elegans) 3 (RBFOX3) antibody (ABIN6566704) Western blot analysis of extracts of various cell lines, using RBFOX3 antibody.
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