TLR7 antibody (Toll-Like Receptor 7)

Details for Product anti-TLR7 Antibody No. ABIN6566727
Antigen
Reactivity
Human, Mouse (Murine)
204
108
35
3
3
3
2
1
1
1
1
Host
Rabbit
197
32
2
1
Clonality
Polyclonal
Conjugate
This TLR7 antibody is un-conjugated
15
14
9
7
6
6
4
4
4
4
4
4
2
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (IHC)
165
91
67
35
31
13
11
10
7
5
2
2
2
Options
Immunogen Recombinant protein of human TLR7
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name TLR7 (TLR7 Antibody Abstract)
Background

Synonyms: PRO285,TLR 7,Tlr7,TLR7,Toll like receptor 7,Toll-like receptor 7,UNQ248

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.

Molecular Weight

Calculated_MW: 120kDa

Gene ID 51284
UniProt Q9NYK1
Pathways TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
Application Notes IHC 1:50 - 1:200 IF 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Toll-Like Receptor 7 (TLR7) antibody (ABIN6566727) Immunohistochemistry of paraffin-embedded human thyroid cancer using TLR7 Antibody.
Image no. 2 for anti-Toll-Like Receptor 7 (TLR7) antibody (ABIN6566727) Immunofluorescence analysis of MCF-7 cells using TLR7 antibody.