YAP1 antibody (Yes-Associated Protein 1)

Details for Product anti-YAP1 Antibody No. ABIN6566736
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
242
125
113
9
6
6
5
4
3
3
3
3
3
1
Host
Rabbit
199
40
8
1
Clonality
Polyclonal
Conjugate
This YAP1 antibody is un-conjugated
10
7
7
7
7
7
7
7
5
5
5
5
2
2
2
2
2
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
179
100
70
46
45
31
26
20
16
11
5
4
3
3
2
2
Options
Immunogen Recombinant protein of human YAP1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name YAP1 (YAP1 Antibody Abstract)
Background

Synonyms: 65 kDa Yes associated protein,65 kDa Yes-associated protein,COB1,YAp 1,YAP 65,YAP,YAP1,YAP1,YAP2,YAP65,yes -associated protein delta,Yes associated protein 1 65  kDa,Yes associated protein 1,Yes associated protein 2,yes associated protein beta,YKI,Yorkie homolog

Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight

Observed_MW: 72kDa

Calculated_MW: 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa

Gene ID 10413
UniProt P46937
Pathways MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Yes-Associated Protein 1 (YAP1) antibody (ABIN6566736) Western blot analysis of extracts of various cell lines, using YAP1 antibody.
Image no. 2 for anti-Yes-Associated Protein 1 (YAP1) antibody (ABIN6566736) Immunohistochemistry of paraffin-embedded human stomach using YAP1 antibody.