ADAM22 antibody

Catalog No. ABIN6566748

Product Details anti-ADAM22 Antibody

Target: ADAM22 (ADAM Metallopeptidase Domain 22 (ADAM22))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM22 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ADAM22

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:4000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADAM22

Target: ADAM22 (ADAM Metallopeptidase Domain 22 (ADAM22))

Alternative Name: ADAM22 (ADAM22 Products)

Synonyms: 2900022I03Rik antibody, AI854032 antibody, MDC2 antibody, ADAM 22 antibody, mdc11b antibody, mdc2 antibody, a disintegrin and metallopeptidase domain 22 antibody, ADAM metallopeptidase domain 22 antibody, ADAM metallopeptidase domain 22 L homeolog antibody, Adam22 antibody, ADAM22 antibody, adam22.L antibody

Background:

Synonyms: A disintegrin and metalloproteinase domain 22,ADA22,ADAM 22,ADAM metallopeptidase domain 22,adam22,and cysteine-rich protein 2,Disintegrin and metalloproteinase domain-containing protein 22,disintegrin-like,MDC 2,MDC2,Metalloproteinase disintegrin ADAM22 3,Metalloproteinase like disintegrin like and cysteine rich protein 2,Metalloproteinase-disintegrin ADAM22-3,Metalloproteinase-like,MGC149832

Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

Molecular Weight:

Observed_MW: 100kDa

Calculated_MW: 91kDa/95kDa/96kDa/100kDa

Gene ID: 53616

UniProt: Q9P0K1