Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2) antibody

Details for Product No. ABIN6566826
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
69
32
20
15
1
1
Host
Rabbit
86
15
Clonality
Polyclonal
Conjugate
Un-conjugated
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Western Blotting (WB)
62
54
21
20
17
16
11
4
2
1
1
Options
Immunogen Recombinant protein of human SLC11A2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name SLC11A2 (SLC11A2 Antibody Abstract)
Background

Synonyms: DCT 1,dct-1,DCT1,Divalent cation transporter 1,Divalent metal transporter 1,DMT 1,DMT-1,DMT1,FLJ37416,Natural resistance associated macrophage protein 2,Natural resistance-associated macrophage protein 2,NRAM2,NRAMP 2,NRAMP2,OK/SW-cl.20,Slc11a2,Solute carrier family 11 (proton coupled divalent metal ion transporters) member 2,Solute carrier family 11 member 2

Background: This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 75kDa

Calculated_MW: 61kDa/62kDa/64kDa/65kDa

Gene ID 4891
UniProt P49281
Pathways Transition Metal Ion Homeostasis, Proton Transport, Positive Regulation of Endopeptidase Activity
Application Notes WB 1:1000 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2) antibody (ABIN6566826) Western blot analysis of extracts of various cell lines, using SLC11A2 antibody.