MMACHC antibody (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria)

Details for Product anti-MMACHC Antibody No. ABIN6566890
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
59
10
7
2
2
2
2
2
2
1
1
1
Host
Rabbit
39
22
Clonality
Polyclonal
Conjugate
This MMACHC antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
58
20
17
8
5
4
3
2
1
1
Options
Immunogen Recombinant protein of human MMACHC
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name MMACHC (MMACHC Antibody Abstract)
Background

Synonyms: 1810037K07Rik,BOS_3654,cblC,DKFZp564I122,FLJ25671,Methylmalonic aciduria (cobalamin deficiency) cblC type with homocystinuria,Methylmalonic aciduria and homocystinuria type C protein,Methylmalonic aciduria and homocystinuria type C protein homolog,MGC134307,MMAC,MMACHC,OTTHUMP00000009243,RP11 291L19.3,RP23-177C18.3

Background: The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.

Molecular Weight

Observed_MW: 32kDa

Calculated_MW: 31kDa

Gene ID 25974
UniProt Q9Y4U1
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC) antibody (ABIN6566890) Western blot analysis of extracts of various cell lines, using MMACHC antibody.