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MMACHC antibody
MMACHC
Reactivity: Human, Mouse, Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MMACHC Antibody
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Target
See all MMACHC Antibodies
MMACHC
(Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))
Reactivity
All reactivities for MMACHC antibodies
Human, Mouse, Rat
Host
All hosts for MMACHC antibodies
Rabbit
Clonality
All clonalities for MMACHC antibodies
Polyclonal
Conjugate
All conjugates for MMACHC antibodies
This MMACHC antibody is un-conjugated
Application
All applications for MMACHC antibodies
Western Blotting (WB), ELISA
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
methylmalonic aciduria(cobalamin deficiency) cblC type, with homocystinuria
Isotype
IgG
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Discover our top product MMACHC Primary Antibody
Alternatives
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anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC) (AA 190-239) antibody
MMACHC
Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Bat, Monkey, Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB: 1:500-1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for MMACHC
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Target
MMACHC
(Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))
Alternative Name
MMACHC (MMACHC Products )
Synonyms
cblC antibody, RP11-291L19.3 antibody, RGD1310806 antibody, 1810037K07Rik antibody, methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria antibody, methylmalonic aciduria cblC type, with homocystinuria antibody, MMACHC antibody, Mmachc antibody
Background
Synonyms: Background:Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate(PubMed:19700356, PubMed:21697092, PubMed:22642810). Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione-dependent reductive demethylation of adenosylcobalamin(PubMed:19801555, PubMed:22642810, PubMed:25809485). Under anaerobic conditions cob(I)alamin is the first product, it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen(PubMed:19801555). Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives(PubMed:21071249).
Molecular Weight
32 kDa
Gene ID
25974
UniProt
Q9Y4U1
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