Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) antibody

Details for Product No. ABIN6566907
Antigen
Reactivity
Human, Mouse (Murine)
40
9
6
Host
Rabbit
39
1
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
39
20
9
8
4
2
2
2
1
1
Options
Immunogen Recombinant protein of human PPFIA1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name PPFIA1 (PPFIA1 Antibody Abstract)
Background

Synonyms: FLJ42630,HGNC:9245,LAR interacting protein 1,LAR-interacting protein 1,LIP 1,LIP-1,LIP.1,LIP1,LIPA1,LIPRIN,Liprin-alpha-1,MGC26800,PPFIA 1,PPFIA1,Protein tyrosine phosphatase receptor type f polypeptide (PTPRF) interacting protein (liprin) alpha 1,Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 1,Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1,PTPRF interacting protein alpha 1,PTPRF-interacting protein alpha-1

Background: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Molecular Weight

Observed_MW: 140kDa

Calculated_MW: 133kDa/135kDa

Gene ID 8500
UniProt Q13136
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) antibody (ABIN6566907) Western blot analysis of extracts of various cell lines, using PPFIA1 antibody.