PPFIA1 antibody

Catalog No. ABIN6566907

Product Details anti-PPFIA1 Antibody

Target: PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPFIA1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PPFIA1 (NP_003617.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPFIA1

Target: PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))

Alternative Name: PPFIA1 (PPFIA1 Products)

Synonyms: LIP.1 antibody, LIP1 antibody, LIPRIN antibody, C030014K08Rik antibody, C87158 antibody, PTPRF interacting protein alpha 1 antibody, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 antibody, PPFIA1 antibody, Ppfia1 antibody

Background: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Molecular Weight:

Observed_MW: 140kDa

Calculated_MW: 133kDa/135kDa

Gene ID: 8500

UniProt: Q13136