DVL1 antibody (Dishevelled, Dsh Homolog 1 (Drosophila))

Details for Product anti-DVL1 Antibody No. ABIN6566969
Antigen
Reactivity
Mouse (Murine), Rat (Rattus)
62
34
29
9
3
3
3
2
2
1
1
1
Host
Rabbit
61
8
3
Clonality
Polyclonal
Conjugate
This DVL1 antibody is un-conjugated
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Western Blotting (WB)
55
30
24
17
13
8
7
2
1
1
1
1
Options
Immunogen Recombinant protein of human DVL1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name DVL1 (DVL1 Antibody Abstract)
Background

Synonyms: Dishevelled 1,dishevelled 1 like,Dishevelled,Dishevelled dsh homolog 1,Dishevelled-1,Dishevelled1,DSH homolog 1,Dvl 1,Dvl,Dvl1,DVL1,DVL1L1,MGC54245,Segment polarity protein dishevelled homolog DVL 1,segment polarity protein dishevelled homolog DVL 1 like,Segment polarity protein dishevelled homolog DVL-1,Segment polarity protein dishevelled homolog DVL1

Background: DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

Molecular Weight

Observed_MW: 90kDa

Calculated_MW: 72kDa/75kDa

Gene ID 1855
UniProt O14640
Pathways WNT Signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Dishevelled, Dsh Homolog 1 (Drosophila) (DVL1) antibody (ABIN6566969) Western blot analysis of extracts of various cell lines, using DVL1 antibody.