P4HA1 antibody (Prolyl 4-Hydroxylase, alpha Polypeptide I)

Details for Product anti-P4HA1 Antibody No. ABIN6566970
Antigen
Reactivity
Human
46
11
8
4
3
3
2
2
1
1
Host
Rabbit
37
7
4
Clonality
Polyclonal
Conjugate
This P4HA1 antibody is un-conjugated
4
4
4
3
3
3
Application
Western Blotting (WB)
45
31
11
2
2
1
1
Options
Immunogen Recombinant protein of human P4HA1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name P4HA1 (P4HA1 Antibody Abstract)
Background

Synonyms: 2-oxoglutarate-4-dioxygenase subunit alpha-1,4-hydroxylase,alpha I subunit,4-PH alpha-1,P4HA,P4HA1,P4HA1,Procollagen-proline,Procollagen-proline,2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase),alpha polypeptide I,Prolyl 4-hydroxylase subunit alpha-1

Background: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight

Observed_MW: 60kDa

Calculated_MW: 58kDa/60kDa/61kDa

Gene ID 5033
UniProt P13674
Application Notes WB 1:1000 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) antibody (ABIN6566970) Western blot analysis of extracts of various cell lines, using P4HA1 antibody.