Melanoma Antigen Family D, 1 (MAGED1) antibody

Details for Product No. ABIN6567039
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
93
55
53
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
86
11
2
Clonality
Polyclonal
Conjugate
Un-conjugated
6
4
4
4
4
4
4
3
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
71
41
37
13
8
5
3
2
2
1
1
Options
Immunogen Recombinant protein of human MAGED1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name MAGED1 (MAGED1 Antibody Abstract)
Background

Synonyms: DLXIN 1,MAGD1,MAGE D1 antigen,MAGE tumor antigen CCF,MAGE-D1 antigen,Maged1,Melanoma antigen family D 1,Melanoma associated antigen D1,Melanoma-associated antigen D1,Neurotrophin receptor interacting MAGE homolog,Neurotrophin receptor-interacting MAGE homolog,NRAGE,PP2250

Background: This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 86KD

Calculated_MW: 86kDa/91kDa

Gene ID 9500
UniProt Q9Y5V3
Pathways Neurotrophin Signaling Pathway
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Melanoma Antigen Family D, 1 (MAGED1) antibody (ABIN6567039) Western blot analysis of extracts of various cell lines, using MAGED1 antibody.
Image no. 2 for anti-Melanoma Antigen Family D, 1 (MAGED1) antibody (ABIN6567039) Immunohistochemistry of paraffin-embedded human liver cancer using MAGED1 antibody.