MLL5/KMT2E antibody (N-Term)

Catalog No. ABIN658094

Product Details anti-MLL5/KMT2E Antibody

Target: MLL5/KMT2E (MLL5) (Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5))

Binding Specificity: AA 93-120, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLL5/KMT2E antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MLL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human MLL5.

Clone: RB19215

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MLL5 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-MLL5/KMT2E antibody (ABIN658094)

Zhou, Wang, Yuan, Zhou, Liu, Wan, Zhang, Ding, Wang, Xiong, Wang, Yuan, Li, Zhang: "Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1)." in: The Journal of biological chemistry, Vol. 288, Issue 24, pp. 17532-43, (2013) (PubMed).

Target Details for MLL5/KMT2E

Target: MLL5/KMT2E (MLL5) (Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5))

Alternative Name: MLL5 (MLL5 Products)

Synonyms: HDCMC04P antibody, MLL5 antibody, 1810033J14Rik antibody, 9530077A04Rik antibody, D230038D11Rik antibody, Mll5 antibody, lysine methyltransferase 2E antibody, lysine (K)-specific methyltransferase 2E antibody, KMT2E antibody, Kmt2e antibody

Background: This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized. [provided by RefSeq].

Molecular Weight: 204965

Gene ID: 55904

NCBI Accession: NP_061152, NP_891847

UniProt: Q8IZD2

Pathways: Retinoic Acid Receptor Signaling Pathway, Warburg Effect