RPS6KA2 antibody (C-Term)

Catalog No. ABIN6655209

Supplier Product No.: 600-401-e30

Product Details anti-RPS6KA2 Antibody

Target: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KA2 antibody is un-conjugated

Application: Western Blotting (WB)

Supplier Product No.: 600-401-e30

Supplier: Rockland

Purpose: p90 RSK2 Antibody

Cross-Reactivity (Details): Anti-p90 RSK2 antibody is directed against mouse p90 RSK2 protein.

Purification: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-p90 RSK2 Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the C-terminal region.

Isotype: IgG

Application Details

Application Notes:

Western_Blot_Dilution: 1:1000

Other: User Optimized

Comment:

Anti-p90 RSK2 Antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 90 kDa in size corresponding to the RSK protein in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for RPS6KA2

Target: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Alternative Name: RPS6KA2 (RPS6KA2 Products)

Background:

Synonyms: p90 RSK2, Ribosomal S6 Kinase 2, RSK2, S6K-alpha 2, 90 kDa Ribosomal Protein S6 Kinase 2, MAP kinase-activated protein kinase 2a, or MAPKAPK2A

Background: p90 RSK2 Antibody detects p90 RSK2 protein. The p90 ribosomal S6 kinases (RSK)1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits. Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling. RSK1 is studied in cancer research and is known to inactive tumor supressor complexes and death kinases. Anti-p90 RSK1 Antibody is ideal for investigators involved in Neuroscience, Cell Signaling, and Cancer research.

Gene Name: RPS6KA2

Gene ID: 6196

UniProt: Q15349

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades