SCN2A antibody (C-Term)
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- Target See all SCN2A Antibodies
- SCN2A (Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))
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Binding Specificity
- C-Term
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SCN2A antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
- Supplier Product No.
- 200-301-g19
- Supplier
- Rockland
- Purpose
- Nav1.2 Antibody
- Purification
- Anti-Nav1.2 Antibody was purified by Protein G chromatography.
- Sterility
- Sterile filtered
- Immunogen
- Nav1.2 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to the cytoplasmic C-terminus region of rat Nav1.2.
- Clone
- S69-3
- Isotype
- IgG2a
- Top Product
- Discover our top product SCN2A Primary Antibody
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- Application Notes
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Immunoprecipitation_Dilution: User Optimized
Immunohistochemistry_Dilution: 0.1-1.0 μg/mL
IF_Microscopy_Dilution: 1.0-10 μg/mL
Western_Blot_Dilution: 1 μg/mL
- Comment
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Anti-Nav1.2 Antibody is tested for use in WB, IP, and IHC. Expect a band approximately ~250kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.09 % (w/v) Sodium Azide - Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Expiry Date
- 12 months
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- Target
- SCN2A (Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))
- Alternative Name
- Nav1.2 (SCN2A Products)
- Background
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Synonyms: SCN, SCN2A, ScpII, NachII, Nav1.2, Scn2a2, RII/RIIA, RNSCPIIR, Scn2a1, Sodium channel protein type 2 subunit alpha, Sodium channel protein brain II subunit alpha, Sodium channel protein type II subunit alpha, Voltage-gated Sodium channel subunit alpha Nav1.2
Background: Nav1.2 is a protein that in humans is encoded by the SCN2A gene. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. Neuronal Nav1.2 channels are therapeutic targets in seizure, pain and stroke.
Gene Name: Scn2a
- Gene ID
- 24766
- NCBI Accession
- NP_036779
- UniProt
- P04775
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