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SCN2A antibody (C-Term)

Rockland 200-301-g19 SCN2A Reactivity: Rat IHC, WB, IP, FM Host: Mouse Monoclonal S69-3 unconjugated
Rockland
Catalog No. ABIN6658123
Supplier Product No.: 200-301-g19
  • Target See all SCN2A Antibodies
    SCN2A (Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))
    Binding Specificity
    • 15
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 29
    • 12
    • 5
    • 1
    Rat
    Host
    • 27
    • 2
    • 1
    Mouse
    Clonality
    • 29
    • 1
    Monoclonal
    Conjugate
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCN2A antibody is un-conjugated
    Application
    • 13
    • 13
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
    Supplier Product No.
    200-301-g19
    Supplier
    Rockland
    Purpose
    Nav1.2 Antibody
    Purification
    Anti-Nav1.2 Antibody was purified by Protein G chromatography.
    Sterility
    Sterile filtered
    Immunogen
    Nav1.2 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to the cytoplasmic C-terminus region of rat Nav1.2.
    Clone
    S69-3
    Isotype
    IgG2a
    Top Product
    Discover our top product SCN2A Primary Antibody
  • Application Notes

    Immunoprecipitation_Dilution: User Optimized

    Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

    IF_Microscopy_Dilution: 1.0-10 μg/mL

    Western_Blot_Dilution: 1 μg/mL

    Comment

    Anti-Nav1.2 Antibody is tested for use in WB, IP, and IHC. Expect a band approximately ~250kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: 0.09 % (w/v) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Expiry Date
    12 months
  • Target
    SCN2A (Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))
    Alternative Name
    Nav1.2 (SCN2A Products)
    Background

    Synonyms: SCN, SCN2A, ScpII, NachII, Nav1.2, Scn2a2, RII/RIIA, RNSCPIIR, Scn2a1, Sodium channel protein type 2 subunit alpha, Sodium channel protein brain II subunit alpha, Sodium channel protein type II subunit alpha, Voltage-gated Sodium channel subunit alpha Nav1.2

    Background: Nav1.2 is a protein that in humans is encoded by the SCN2A gene. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. Neuronal Nav1.2 channels are therapeutic targets in seizure, pain and stroke.

    Gene Name: Scn2a

    Gene ID
    24766
    NCBI Accession
    NP_036779
    UniProt
    P04775
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