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Integrin alpha 4 (ITGA4) (AA 584-609) antibody Primary Antibody

ITGA4 Reactivity: Human, Mouse, Rat, Rabbit FACS, IF (p), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Pubmed (1)
Catalog No. ABIN671301
$339.90
Plus shipping costs $45.00
100 μL
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  • Target
    Binding Specificity
    AA 584-609
    Reactivity
    Human, Mouse, Rat, Rabbit
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    Un-conjugated
    Application
    Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Integrin alpha 4
    Isotype
    IgG
  • Application Notes
    WB 1:100-1000
    FCM 1:20-100
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Lee, Lee, Huang, Chang, Lin, Chien, Yang, Lin: "Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells." in: PLoS ONE, Vol. 9, Issue 11, pp. e111390, 2014 (PubMed). (Sample species: Rabbit).

  • Target
    Alternative Name
    Integrin alpha 4/CD49d (ITGA4 Antibody Abstract)
    Synonyms
    CD49D, IA4, LOC100219853, integrin subunit alpha 4, integrin alpha 4, integrin subunit alpha 4 S homeolog, ITGA4, Itga4, itga4.S
    Background

    Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

    Subcellular location: Extracellular

    Synonyms: IA4, CD49D, Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, VLA-4 subunit alpha, ITGA4

    Gene ID
    3676
    UniProt
    P13612
    Pathways
    Integrin Complex
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