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Fibronectin (AA 1230-1280) antibody (FITC) Primary Antibody

Reactivity: Human, Mouse, Rat IF (cc), IF (p) Host: Rabbit Polyclonal
Pubmed (1)
Catalog No. ABIN671653
$442.20
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100 μL
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  • Target
    Binding Specificity
    AA 1230-1280
    Reactivity
    Human, Mouse, Rat
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    FITC
    Application
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Fibronectin
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4°C
    Expiry Date
    12 months
  • Kang, Baik, Yoo, Kim, Cheong, Park, Kang, Ha: "Aliskiren Regulates Neonatal Fc Receptor and IgG Metabolism with Attenuation of Anti-GBM Glomerulonephritis in Mice." in: Nephron, Vol. 134, Issue 4, pp. 272-282, 2016 (PubMed). Method employed by authors: Immunofluorescence (IF) (Sample species: Mouse (Murine)). Further details: Sample: kidney

  • Target
    Background

    Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling (By similarity).

    Subcellular location: Secreted

    Synonyms: Fn, Fn-1, E3327I9, Fibronectin, Fn1

    Gene ID
    14268
    UniProt
    P11276
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