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PD-L1 antibody

PD-L1 Reactivity: Human FACS Host: Mouse Monoclonal 29E-2A3 unconjugated
Catalog No. ABIN6727426
  • Target See all PD-L1 Antibodies
    PD-L1 (CD274 (PD-L1))
    Reactivity
    • 167
    • 106
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Human
    Host
    • 126
    • 59
    • 15
    • 4
    • 4
    • 1
    Mouse
    Clonality
    • 108
    • 99
    • 2
    Monoclonal
    Conjugate
    • 97
    • 14
    • 13
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    This PD-L1 antibody is un-conjugated
    Application
    • 137
    • 102
    • 60
    • 40
    • 36
    • 28
    • 17
    • 16
    • 16
    • 15
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    Purified
    Clone
    29E-2A3
    Isotype
    IgG2b, kappa
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Matching Isotype Control: Purified Mouse IgG2b, κ Isotype Control (ABIN7469802)

    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % Proclin300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2~8°C. Do not freeze.
  • Target
    PD-L1 (CD274 (PD-L1))
    Alternative Name
    PD-L1 (PD-L1 Products)
    Synonyms
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    Background
    B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
    Gene ID
    29126
    UniProt
    Q9NZQ7
    Pathways
    Cancer Immune Checkpoints
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