CD14 antibody (CD14 Molecule) (Alexa Fluor 488)

Details for Product anti-CD14 Antibody No. ABIN6728114
Target
Reactivity
Mouse
339
70
36
35
33
32
30
28
25
23
23
22
22
16
15
11
8
6
6
6
3
2
2
2
1
Host
Rat
280
93
18
9
3
Clonality (Clone)
Monoclonal ()
Conjugate
This CD14 antibody is conjugated to Alexa Fluor 488
43
30
30
23
7
5
5
5
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
302
125
89
67
66
60
31
28
23
13
12
6
6
6
5
3
3
3
3
3
2
2
1
1
1
1
1
1
Options
Clone Sa14-2
Isotype IgG2a, kappa
Target
Alternative Name CD14 (CD14 Antibody Abstract)
Background

Synonyms: CD 14,Myeloid cell-specific leucine-rich glycoprotein,Monocyte differentiation antigen CD14

Background: CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

Gene ID 12475
UniProt P10810
Pathways TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.