SLAMF1 antibody (Signaling Lymphocytic Activation Molecule Family Member 1) (APC)

Details for Product anti-SLAMF1 Antibody No. ABIN6728127
Antigen
  • CD150
  • SLAM
  • SLAMF1
  • 4933415F16
  • AA177906
  • CDw150
  • ESTM51
  • IPO-3
  • Slam
  • RGD1560634
  • signaling lymphocytic activation molecule family member 1
  • SLAMF1
  • Slamf1
Reactivity
Mouse (Murine)
181
83
43
2
1
1
1
1
1
1
1
Host
Rat
149
36
30
Clonality (Clone)
Monoclonal ()
Conjugate
This SLAMF1 antibody is conjugated to APC
19
16
14
8
7
6
6
5
5
5
5
4
2
2
2
2
2
Application
Flow Cytometry (FACS)
89
69
63
26
21
18
17
10
9
6
5
4
4
2
1
1
Options
Clone TC15-12F12-2
Isotype IgG2a, lambda
Plasmids, Primers & others Plasmids, Primers & others SLAMF1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD150 (SLAMF1 Antibody Abstract)
Background

Synonyms: Slam,Slamf1,CD 150,Signaling lymphocytic activation molecule

Background: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

Gene ID 27218
UniProt Q9QUM4
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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