IL-10 antibody (Interleukin 10) (APC)

Details for Product anti-IL10 Antibody No. ABIN6728562
Antigen
  • CSIF
  • GVHDS
  • IL-10
  • IL10A
  • TGIF
  • Il-10
  • IL10X
  • interleukin 10
  • IL10
  • Il10
Reactivity
Mouse (Murine)
288
143
92
28
19
15
12
10
9
8
8
6
6
5
3
3
2
2
1
1
Host
Rat
270
131
90
6
4
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This IL-10 antibody is conjugated to APC
61
25
19
14
10
7
4
4
4
4
3
3
3
3
3
3
3
1
1
1
1
1
Application
Flow Cytometry (FACS)
333
304
117
81
52
52
49
39
34
33
25
23
19
13
9
9
6
5
4
4
4
3
3
3
2
1
1
1
1
1
1
1
Options
Clone JES5-16E3
Isotype IgG2b, kappa
Plasmids, Primers & others Plasmids, Primers & others IL-10 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name IL-10 (IL10 Antibody Abstract)
Background

Synonyms: Interleukin-10,IL-10,Cytokine synthesis inhibitory factor,CSIF

Background: L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80 % sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones, inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis, suppresses the delayed type hypersensitivity response, stimulates Th2 cell response (which results in elevated antibody production), and promotes mast cell proliferation in combination with IL-4.

Gene ID 16153
UniProt P18893
Pathways Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Did you look for something else?