PPP3CB antibody (AA 264-283)

Catalog No. ABIN6796480

Product Details anti-PPP3CB Antibody

Target: PPP3CB (Protein Phosphatase 3, Catalytic Subunit, beta Isozyme (PPP3CB))

Binding Specificity: AA 264-283

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Pig, Bat, Monkey, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3CB antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificity: Recognizes an ~61kD protein, corresponding to the apparent molecular mass of recombinant calcineurin A. Species cross-reactivity: Human, mouse, rat, rabbit, canine, Drosophila, hamster, bovine, chicken, monkey, porcine and sheep.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Horse, Pig, Opossum, Platypus, Xenopus (100%) Stickleback, Zebrafish (95%) Orangutan, Hamster, Turkey (90%).

Purification: Immunoaffinity purified

Immunogen: A 20 residue synthetic peptide EDFGNEKSQEHFSHNTVRGC based on the human calcineurin A (residues 264-283) was synthesized and the peptide coupled to KLH. This sequence is identical to rat and mouse calcineurin A over these residues. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Horse, Pig, Opossum, Platypus, Xenopus (100%), Stickleback, Zebrafish (95%), Orangutan, Hamster, Turkey (90%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Application Details

Application Notes: Approved: IP (10 μg/mL), WB (2 μg/mL)

Usage: Suitable for use in Western Blot and Immunoprecipitation. Western Blot (ECL): 0.5 μg/mL. Immunoprecipitation: 10 μg/mL. Positive control: Rat Brain Tissue Extract.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: BBS,  pH 8.4 25 mM sodium borate, 100 mM boric acid, 75 mM sodium chloride, 5 mM EDTA (disodium salt).

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for PPP3CB

Target: PPP3CB (Protein Phosphatase 3, Catalytic Subunit, beta Isozyme (PPP3CB))

Alternative Name: PPP3CB (PPP3CB Products)

Background: Name/Gene ID: PPP3CB
Subfamily: PP2B
Family: Protein Phosphatase

Synonyms: PPP3CB, Calcineurin A2, CALNB, CALNA2, CNA2, Calcineurin A beta, Cna beta, PP2Bbeta, Calcineurin b, CAM-PRP catalytic subunit, Phosphatase 2b beta, pp2b-beta

Gene ID: 5532

UniProt: P16298

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Regulation of Leukocyte Mediated Immunity, VEGF Signaling, BCR Signaling