DEFA4 antibody (AA 41-97) (Biotin)

Catalog No. ABIN680880

Product Details anti-DEFA4 Antibody (Biotin)

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Binding Specificity: AA 41-97

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEFA4 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Defensin alpha 4

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for DEFA4

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Alternative Name: Defensin alpha 4 (DEFA4 Products)

Synonyms: DEF4 antibody, HNP-4 antibody, HP-4 antibody, HP4 antibody, DEFA4 antibody, Crp4 antibody, Defa28 antibody, Defcr4 antibody, defensin alpha 4 antibody, defensin, alpha 4, corticostatin antibody, defensin, alpha, 4 antibody, DEFA4 antibody, Defa4 antibody

Background:

Synonyms: Neutrophil defensin 4, Defensin, alpha 4, HNP-4, HP-4, defensin, alpha 4, corticostatin, neutrophil defensin 4 precursor, neutrophil defensin 4 preproprotein.

Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils, it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq].

Gene ID: 1669