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DEFA4 Products

(Defensin, alpha 4, Corticostatin (DEFA4))
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils\; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Jul 2008].

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Featured DEFA4 Categories

DEFA4 Antibodies

High quality antibodies with extensive validation data.

DEFA4 ELISA Kits

Reliable ELISA kits for a wide range of species.

DEFA4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DEFA4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB, IP, ICC
Validations
  • (7)
Cat. No. ABIN7441130
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (2)
Cat. No. ABIN7443056
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN6261265
Quantity 100 μL
Datasheet Datasheet

Recommended DEFA4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955305
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973801
Quantity 96 tests
Datasheet Datasheet

Recommended DEFA4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406833
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416031
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DEFA4 products

Cerrillo, Moret, Iborra, Ramos, Busó, Tortosa, Sáez-González, Nos, Beltrán: "Alpha-defensins (α-Defs) in Crohn's disease: decrease of ileal α-Def 5 via permanent methylation and increase in plasma α-Def 1-3 concentrations offering biomarker utility." in: Clinical and experimental immunology, (2018) (PubMed).

Synonyms and alternative names related to DEFA4

defensin alpha 4 (DEFA4), defensin, alpha 4, corticostatin (DEFA4), defensin, alpha, 4 (Defa4), Crp4, DEF4, DEFA4, Defa28, Defcr4, HNP-4, HP-4, HP4

Protein level used designations for DEFA4

  • corticostatin
  • defensin, alpha 4, preproprotein
  • neutrophil defensin 4
  • alpha-defensin 4, corticostatin
  • Paneth cell-specific alpha-defensin 4
  • alpha-defensin 4
  • alpha-defensin, 28
  • defensin related cryptdin 4
  • defensin, alpha, 28
  • defensin-related cryptdin-4
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