PD-L1 antibody (AA 39-191)

Catalog No. ABIN6939566

This Mouse Monoclonal antibody specifically detects PD-L1 in ELISA and Coat. It exhibits reactivity toward Human.

Quick Overview for PD-L1 antibody (AA 39-191) (ABIN6939566)

Target: PD-L1 (CD274 (PD-L1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PD-L1 antibody is un-conjugated

Application: ELISA, Coating (Coat)

Clone: PDL1-2741

Product Details anti-PD-L1 Antibody

Binding Specificity: AA 39-191

Purification: Purified by Protein A/G

Immunogen: Recombinant fragment of human CD274 protein (around aa39-191) (exact sequence is proprietary)

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Heart, Placenta, Spleen or Tonsil.

Known Application: ELISA (For coating, order antibody without BSA), ,Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: CD274

Background: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Molecular Weight: 37-50kDa

Gene ID: 29126

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints