Neurofilament, Light Polypeptide (NEFL) (AA 31-130) antibody (Alexa Fluor 594)

Details for Product No. ABIN6944272
Target
Binding Specificity
AA 31-130
14
4
4
4
3
3
2
2
2
2
1
1
1
1
Reactivity
Human, Mouse, Rat
108
68
50
42
37
30
3
3
3
2
2
1
Host
Rabbit
67
49
11
1
1
1
Clonality
Polyclonal
Conjugate
Alexa Fluor 594
10
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
74
53
45
26
26
25
16
16
12
9
7
7
6
6
2
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human NF-L
Isotype IgG
Specificity SNDLKSIRTQEK-Y 80-91/543
Purification Purified by Protein A.
Target
Alternative Name NF-L (NEFL Antibody Abstract)
Background

Neurofilament light polypeptide also called NF-L, Neurofilament triplet L protein, 68 kDa neurofilament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The extra mass and high charge density that distinguish the neurofilament proteins from all other intermediate filament proteins are due to the tailpiece extensions. This region may form a charged scaffolding structure suitable for interaction with other neuronal components or ions. NF-L is the most abundant of the three neurofilament proteins and, as the other nonepithelial intermediate filament proteins, it can form homopolymeric 10-nm filaments. Belongs to the intermediate filament family.


Synonyms: Neurofilament L, Neurofilament 68, Neurofilament triplet L, 70 kD Neurofilament Light, 68 kDa neurofilament protein, CMT 1F, CMT 2E, CMT1F, CMT2E, FLJ53642, Light molecular weight neurofilament protein, NEFL, Neurofilament light, Neurofilament light polypeptide 68 kDa, Neurofilament light polypeptide, Neurofilament protein, light chain, Neurofilament subunit NF L, Neurofilament triplet L protein, NF 68, NF L, NF68, NFL, NFL_HUMAN.
Gene ID 4747
UniProt P07196
Application Notes IF(IHC-P)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Expiry Date 12 months