NEFL antibody
Quick Overview for NEFL antibody (ABIN1108416)
Target
See all NEFL AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody reacts to NEFL.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Purified
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, 0.05 % sodium azide, 0,5 % BSA
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- NEFL (Neurofilament, Light Polypeptide (NEFL))
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Alternative Name
- Neurofilament L (68kDa)
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Background
- Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.Synonyms: 68 kDa neurofilament protein, NEFL, NF-L, NF68, Neurofilament L
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Molecular Weight
- 62 kDa
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Gene ID
- 4747
Target
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