NR4A1 antibody (Nuclear Receptor Subfamily 4, Group A, Member 1)

Details for Product anti-NR4A1 Antibody No. ABIN6944344
Target
Reactivity
Human, Mouse, Rat
115
53
51
12
10
10
9
6
6
4
2
2
2
2
1
1
1
1
Host
Rabbit
105
8
6
Clonality (Clone)
Monoclonal ()
Conjugate
This NR4A1 antibody is un-conjugated
7
6
4
4
4
3
3
3
3
3
3
3
1
1
1
1
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
78
46
25
22
14
11
7
4
4
3
2
2
1
1
Options
Immunogen N terminus human NUR77
Clone 1C1
Isotype IgG
Purification Purified by Protein A.
Target
Alternative Name NUR77 (NR4A1 Antibody Abstract)
Background

Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.


Synonyms: Nuclear receptor subfamily 4 group A member 1, Early response protein NAK1, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST-59, Testicular receptor 3Nuclear hormone receptor NUR/77, Nur77
Gene ID 3164
UniProt P22736
Pathways Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Application Notes WB(1:300-1000), IHC-P(1:200-400), IF(ICC)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months