NR4A2 antibody (Nuclear Receptor Subfamily 4, Group A, Member 2) (AA 331-430)

Details for Product anti-NR4A2 Antibody No. ABIN6944346
Target
Binding Specificity
AA 331-430
6
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
42
16
12
6
6
5
5
5
5
3
2
2
2
2
2
1
1
Host
Rabbit
39
5
Clonality
Polyclonal
Conjugate
This NR4A2 antibody is un-conjugated
3
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
35
17
15
7
5
3
2
1
1
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human Nurr1
Isotype IgG
Purification Purified by Protein A.
Target
Alternative Name Nurr1 (NR4A2 Antibody Abstract)
Background

Nuclear receptor and transcription factor, plays a role in development and maintenance of neurons synthesizing the neurotransmitter dopamine This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.


Synonyms: Nur-ralated factor 1, Nuclear receptor-related factor 1, Orphan nuclear receptor NR4A2, Orphan nuclear receptor NURR1, Regenerating liver nuclear receptor 1, RNR-1, SL-322, Nuclear orphan receptor HZF-3, T-cell nuclear receptor NOT,HZF 3, HZF3, Immediate-early response protein NOT, Intermediate early receptor protein, NGFI B/nur77 beta type transcription factor homolog, NOT, NR4A2, NR4A2_HUMAN, Nuclear receptor subfamily 4 group A member 2, Nur related protein 1 homolog, Nurr 1,RNR 1, RNR1, TINUR, Transcriptionally inducible nuclear receptor, Transcriptionally inducible nuclear receptor related, Transcriptionally inducible nuclear receptor related 1, Transcriptionally-inducible nuclear receptor.
Gene ID 4929
UniProt P43354
Pathways Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway
Application Notes WB(1:300-1000)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months