p38 antibody (MAP kinase p38)

Details for Product anti-p38 Antibody No. ABIN6944381
Antigen
  • CSBP
  • CSBP1
  • CSBP2
  • CSPB1
  • EXIP
  • Mxi2
  • PRKM14
  • PRKM15
  • RK
  • SAPK2A
  • p38
  • p38ALPHA
  • CRK1
  • Csbp1
  • Csbp2
  • Exip
  • Hog
  • Prkm14
  • Prkm15
  • Sapk2A
  • p38Hog
  • p38alpha
  • Crk1
  • p38-alpha
  • p38MAPK
  • p38a
  • MAP kinase 14A
  • MAP kinase p38a
  • MAPK 14A
  • MAPK14
  • fk28c03
  • hm:zeh1243
  • wu:fk28c03
  • zp38a
  • mitogen-activated protein kinase 14
  • mitogen activated protein kinase 14
  • mitogen-activated protein kinase 14a
  • MAPK14
  • Mapk14
  • mapk14a
Reactivity
Human, Mouse (Murine), Rat (Rattus)
287
249
235
43
28
27
27
27
26
25
24
24
15
15
1
1
Host
Rabbit
243
43
2
Clonality (Clone)
Monoclonal ()
Conjugate
This p38 antibody is un-conjugated
10
7
7
7
7
7
7
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)
209
134
90
78
58
36
28
24
18
18
12
6
5
2
1
1
1
1
1
Options
Immunogen Recombinant human p38 between 150 to 250 amino acids.
Clone 2H4
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name p38 (p38 Antibody Abstract)
Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]


Synonyms: Mitogen-activated protein kinase 14, Cytokine suppressive anti-inflammatory drug-binding protein, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, Stress-activated protein kinase 2a, MAP kinase 14, MAPK 14, CSAID-binding protein, CSBP, MAP kinase p38 alpha, SAPK2a
Gene ID 1432
UniProt Q16539
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling
Application Notes WB(1:300-1000), IF(ICC)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Did you look for something else?