Cadherin pan antibody (Cadherin Pan)

Details for Product anti-Cadherin Pan Antibody No. ABIN6944414
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
32
31
31
7
4
4
Host
Rabbit
29
6
Clonality (Clone)
Monoclonal ()
Conjugate
This Cadherin pan antibody is un-conjugated
3
3
3
3
3
3
3
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Western Blotting (WB)
10
5
5
2
2
2
2
2
1
1
Options
Immunogen C-terminus human Cadherin
Clone 9A1
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name Pan-Cadherin
Background

Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as -catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin, R-cadherin, B-cadherin, E/P cadherin and cadherin-5.


Synonyms: Cadherin-1, CAM 120/80, Epithelial cadherin, Uvomorulin, CD_antigen: CD324, Cadherin-2, CDw325, Neural cadherin, CD_antigen: CD325, Cadherin-3, Placental cadherin, 7B4 antigen, Vascular endothelial cadherin, CD_antigen: CD144, Cadherin-4, Retinal cadherin, E-cadherin, CDH1, CDHE, UVO, CDH2, CDHN, NCAD, P-cadherin, CDH3, CDHP, VE-cadherin, CDH5, R-CAD, R-cadherin
UniProt P12830, P19022, P22223
Application Notes WB(1:300-1000), FCM(1:20-100), IF(ICC)(1:50-200), IHC()
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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