PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (cleaved)

Details for Product anti-PARP1 Antibody No. ABIN6944421
Antigen
  • ADPRT
  • ADPRT 1
  • ADPRT1
  • ARTD1
  • PARP
  • PARP-1
  • PPOL
  • pADPRT-1
  • Adprt
  • Parp-1
  • 5830444G22Rik
  • AI893648
  • Adprp
  • Adprt1
  • C80510
  • parp-1
  • sPARP-1
  • BEST:LD21673
  • CG17685
  • CG17696
  • CG17718
  • CG40411
  • D.PARP
  • Dm.pARTa
  • Dmel\\CG40411
  • LD21673.3prime
  • PARP1
  • dPARP
  • parp
  • adprt1
  • padprt-1
  • ppol
  • si:dkey-206f10.3
  • wu:fc60f12
  • zgc:110092
  • poly(ADP-ribose) polymerase 1
  • poly (ADP-ribose) polymerase 1
  • poly (ADP-ribose) polymerase family, member 1
  • Poly-(ADP-ribose) polymerase
  • poly(ADP-ribose) polymerase 1 L homeolog
  • PARP1
  • Parp1
  • Parp
  • parp1.L
  • parp1
Epitope
cleaved
52
45
37
17
17
17
17
17
17
17
16
16
16
16
16
14
12
12
12
11
10
8
7
6
6
6
5
4
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
533
183
146
18
17
12
9
9
7
7
6
3
2
2
1
1
1
1
1
1
1
Host
Rabbit
487
87
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This PARP1 antibody is un-conjugated
33
27
25
25
25
24
9
9
9
9
9
9
3
3
3
3
3
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)
333
275
150
86
51
47
40
38
31
31
20
9
5
5
5
4
2
1
1
Options
Immunogen Synthetic peptide within Human PARP1 aa 150-250
Clone 2A10
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PARP1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PARP (PARP1 Antibody Abstract)
Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].


Synonyms: Poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase diphtheria toxin-like 1, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthase 1, PARP-1, ARTD1, ADPRT 1, PARP1
Gene ID 142
UniProt P09874
Pathways Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Application Notes WB(1:300-1000), FCM(1:20-100), IF(ICC)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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