PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (AA 580-630) (Cy7)

Details for Product anti-PARP1 Antibody No. ABIN6944435
Antigen
  • ADPRT
  • ADPRT 1
  • ADPRT1
  • ARTD1
  • PARP
  • PARP-1
  • PPOL
  • pADPRT-1
  • Adprt
  • Parp-1
  • 5830444G22Rik
  • AI893648
  • Adprp
  • Adprt1
  • C80510
  • parp-1
  • sPARP-1
  • BEST:LD21673
  • CG17685
  • CG17696
  • CG17718
  • CG40411
  • D.PARP
  • Dm.pARTa
  • Dmel\\CG40411
  • LD21673.3prime
  • PARP1
  • dPARP
  • parp
  • adprt1
  • padprt-1
  • ppol
  • si:dkey-206f10.3
  • wu:fc60f12
  • zgc:110092
  • poly(ADP-ribose) polymerase 1
  • poly (ADP-ribose) polymerase 1
  • poly (ADP-ribose) polymerase family, member 1
  • Poly-(ADP-ribose) polymerase
  • poly(ADP-ribose) polymerase 1 L homeolog
  • PARP1
  • Parp1
  • Parp
  • parp1.L
  • parp1
Epitope
AA 580-630
52
44
38
17
17
17
17
17
17
17
16
16
16
16
16
14
12
12
12
11
10
8
7
6
6
6
5
4
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
533
182
145
18
17
12
9
9
7
7
6
3
2
2
1
1
1
1
1
1
1
Host
Rabbit
487
87
1
1
Clonality
Polyclonal
Conjugate
This PARP1 antibody is conjugated to Cy7
33
27
25
25
25
24
9
9
9
9
9
9
3
3
3
3
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
334
275
150
86
51
47
39
38
32
31
20
9
6
5
5
4
2
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human PARP1
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PARP1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PARP1 (PARP1 Antibody Abstract)
Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].


Synonyms: ADP ribosyltransferase (NAD+, poly (ADP ribose) polymerase), ADP ribosyltransferase NAD+, ADPRT 1, ADPRT, ADPRT1, msPARP, NAD(+) ADP ribosyltransferase 1, pADPRT 1, pADPRT1, PARP 1, PARP1, PARP-1, Poly (ADP ribose) polymerase 1, poly (ADP ribose) polymerase family, member 1, Poly adenosine diphosphate ADP ribose polymerase, Poly ADP ribose polymerase 1, Poly ADP ribose polymerase family member 1, Poly ADP ribose synthetase 1, poly(ADP ribose) synthetase, poly(ADP ribosyl)transferase, Poly[ADP ribose] synthetase 1, PPOL, sPARP 1, sPARP1, PARP1_HUMAN.
Gene ID 142
UniProt P09874
Pathways Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Application Notes IF(IHC-P)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Expiry Date 12 months
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