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PD-L1 antibody

PD-L1 Reactivity: Human WB, FACS Host: Rabbit Monoclonal 6C8 unconjugated

Catalog No. ABIN6944458

Datasheet as PDF

Target See all PD-L1 Antibodies

PD-L1 (CD274 (PD-L1))
Reactivity
168

106

63

7

6

5

5

1

1
Human
Host
127

59

15

4

4

1
Rabbit
Compatible Secondaries
Clonality
108

100

2
Monoclonal
Conjugate
98

14

13

11

8

5

5

5

5

5

5

5

4

4

4

4

4

3

3

2

1

1

1
This PD-L1 antibody is un-conjugated
Application
138

102

60

40

37

28

17

16

16

15

10

7

5

4

3

3

2

2

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity

Human

Purification

Purified by Protein A.

Immunogen

Recombinant human PD-L1 extracellular domain

Clone

6C8

Isotype

IgG

Top Product

Discover our top product PD-L1 Primary Antibody
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reactivity: Human WB, FACS, ELISA, IF Host: Goat Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 Reactivity: Human, Mouse WB, FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (Extracellular Domain) antibody
PD-L1 Reactivity: Human IHC Host: Rabbit Monoclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC Host: Mouse Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 Reactivity: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
FCM 1:20-100

Restrictions

For Research Use only
Format

Liquid

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C for 12 months.

Expiry Date

12 months
Target

PD-L1 (CD274 (PD-L1))

Alternative Name

PD-L1 (PD-L1 Products)

Synonyms

B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody

Background

Synonyms: Programmed cell death 1 ligand 1, CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1, Programmed death ligand 1
Background: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077).

Gene ID

29126

UniProt

Q9NZQ7

Pathways

Cancer Immune Checkpoints