PGC1 alpha + beta (AA 760-798) antibody (Alexa Fluor 680)

Details for Product No. ABIN6944538
Antigen
Epitope
AA 760-798
5
Reactivity
Human, Mouse (Murine), Rat (Rattus)
27
27
27
12
12
12
Host
Rabbit
27
Clonality
Polyclonal
Conjugate
Alexa Fluor 680
4
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
15
6
3
Options
Immunogen KLH conjugated synthetic peptide derived from human PPARGC1A
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name PGC1 alpha , beta
Background

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene.

Subcellular location: Cytoplasm, Nucleus


Synonyms: LEM6, PGC-1 Alpha, PGC1 Alpha, Ligand effect modulator 6, Peroxisome prolerative activated receptor, gamma, coactivator 1 alpha, Peroxisome prolerative activated receptor, gamma, coactivator 1 , Peroxisome prolerator activated receptor gamma coactivator 1 alpha, PGC 1 alpha, PGC 1 alpha, PGC 1v, PGC1, PGC1alpha, PGC1A, PGC1v, PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6, PPAR gamma coactivator 1 alpha, PPAR gamma coactivator 1, PPAR gamma coactivator variant form, PPARGC 1 alpha, PPARGC1A.
Gene ID 10891
UniProt Q9UBK2
Application Notes IF(IHC-P)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Expiry Date 12 months
Did you look for something else?