CAZIP antibody (C-Term)

Catalog No. ABIN6991290

Product Details anti-CAZIP Antibody

Target: CAZIP (MTUS2) (Microtubule-associated Tumor Suppressor Candidate 2 (MTUS2))

Binding Specificity: AA 1300-1350, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAZIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: CAZIP Antibody is affinity chromatography purified via peptide column.

Immunogen: CAZIP antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human CAZIP. The immunogen is located within amino acids 1300 - 1350 of CAZIP.

Isotype: IgG

Application Details

Application Notes: CAZIP antibody can be used for detection of CAZIP by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CAZIP Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CAZIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CAZIP

Target: CAZIP (MTUS2) (Microtubule-associated Tumor Suppressor Candidate 2 (MTUS2))

Alternative Name: CAZIP (MTUS2 Products)

Synonyms: KIAA0774 antibody, DKFZp468L0812 antibody, CAZIP antibody, ICIS antibody, TIP150 antibody, 5730592G18Rik antibody, A730013O20Rik antibody, AU067634 antibody, C130038G02Rik antibody, Cazip antibody, Gm763 antibody, mKIAA0774 antibody, microtubule associated tumor suppressor candidate 2 antibody, microtubule associated scaffold protein 2 antibody, MTUS2 antibody, Mtus2 antibody

Background: CAZIP Antibody: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.

Gene ID: 23281

NCBI Accession: NP_001028774

UniProt: Q5JR59