IDO2 antibody

Catalog No. ABIN7245806

Product Details anti-IDO2 Antibody

Target: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDO2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Full length fusion protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IDO2

Target: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Alternative Name: IDO2 (IDO2 Products)

Synonyms: INDOL1 antibody, Indol1 antibody, AI265623 antibody, C230043N17Rik antibody, Ido-2 antibody, indoleamine 2,3-dioxygenase 2 antibody, IDO2 antibody, Ido2 antibody

Background: INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 45 kDa

UniProt: Q6ZQW0