IDO2 antibody (AA 1-20)

Catalog No. ABIN3031295

Product Details anti-IDO2 Antibody

Target: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Binding Specificity: AA 1-20

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDO2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Amino acids 1-20 (MLHFHYYDTSNKIMEPHRPN-human) were used as the immunogen for this INDOL1 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the INDOL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the INDOL1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for IDO2

Target: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Alternative Name: INDOL1 (IDO2 Products)

Synonyms: INDOL1 antibody, Indol1 antibody, AI265623 antibody, C230043N17Rik antibody, Ido-2 antibody, indoleamine 2,3-dioxygenase 2 antibody, IDO2 antibody, Ido2 antibody

Background: IDO2 (Indoleamine 2,3-dioxygenase 2), also called Indoleamine 2,3-dioxygenase-like 1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer.

UniProt: Q6ZQW0