CHEK2 antibody (pThr68)
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- Target See all CHEK2 Antibodies
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
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Binding Specificity
- pThr68
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHEK2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Characteristics
- Phosphorylated antibody
- Purification
- Affinity purification
- Immunogen
- Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68
- Isotype
- IgG
- Top Product
- Discover our top product CHEK2 Primary Antibody
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anti-Checkpoint Kinase 2 (CHEK2) (pThr387) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibodyCHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibodyCHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibodyCHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (AA 111-141), (N-Term) antibodyCHEK2 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB19067 unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibodyCHEK2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibodyCHEK2 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 4B7 unconjugated
anti-Checkpoint Kinase 2 (CHEK2) antibodyCHEK2 Reactivity: Human, Monkey, Dog WB, IHC, IF, IHC (p), FACS Host: Mouse Monoclonal 10G7 unconjugated
anti-Checkpoint Kinase 2 (CHEK2) antibodyCHEK2 Reactivity: Human, Dog WB, IHC, IF, IHC (p), IP, FACS Host: Mouse Monoclonal 5C4 unconjugated
anti-Checkpoint Kinase 2 (CHEK2) antibodyCHEK2 Reactivity: Human, Dog WB, IHC, IHC (p), IP, FACS Host: Mouse Monoclonal 2H5 unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
- Alternative Name
- CHEK2 (CHEK2 Products)
- Synonyms
- CDS1 antibody, CHK2 antibody, HuCds1 antibody, LFS2 antibody, PP1425 antibody, RAD53 antibody, hCds1 antibody, fa66f08 antibody, wu:fa66f08 antibody, zgc:55865 antibody, Cds1 antibody, HUCDS1 antibody, Rad53 antibody, Chk2 antibody, cds1 antibody, chek2 antibody, chk2 antibody, hucds1 antibody, lfs2 antibody, pp1425 antibody, rad53 antibody, checkpoint kinase 2 antibody, serine/threonine-protein kinase chk2 antibody, checkpoint kinase 2 L homeolog antibody, CHEK2 antibody, chek2 antibody, Chek2 antibody, MCYG_07308 antibody, chek2.L antibody
- Background
- Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
- Molecular Weight
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Observed_MW: 61 kDa
Calculated_MW: 61 kDa
- UniProt
- O96017
- Pathways
- p53 Signaling, Apoptosis, Cell Division Cycle
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