CEBPA antibody
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- Target See all CEBPA Antibodies
- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CEBPA antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CEBPA (NP_004355.2).
- Isotype
- IgG
- Top Product
- Discover our top product CEBPA Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
- Alternative Name
- CEBPA (CEBPA Products)
- Background
- This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.
- Molecular Weight
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Observed_MW: 41 kDa
Calculated_MW: 25 kDa/35 kDa/37 kDa/41 kDa
- Gene ID
- 1050
- UniProt
- P49715
- Pathways
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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