PTPRS antibody

Catalog No. ABIN7264708

Product Details anti-PTPRS Antibody

Target: PTPRS (Protein tyrosine Phosphatase, Receptor Type, S (PTPRS))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRS antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PTPRS (NP_002841.3).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRS

Target: PTPRS (Protein tyrosine Phosphatase, Receptor Type, S (PTPRS))

Alternative Name: PTPRS (PTPRS Products)

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

Molecular Weight:

Observed_MW: 220 kDa

Calculated_MW: 168 kDa/171 kDa/212 kDa/214 kDa/215 kDa/217 kDa

Gene ID: 5802

UniProt: Q13332