BTN1A1 antibody

Catalog No. ABIN7112099

The Rabbit Polyclonal anti-BTN1A1 antibody is suitable to detect BTN1A1 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for BTN1A1 antibody (ABIN7112099)

Target: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTN1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BTN1A1 Antibody

Purpose: BTN1A1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: butyrophilin, subfamily 1, member A1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for BTN1A1

Target: BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))

Alternative Name: BTN1A1

Background:

Synonyms: Butyrophilin subfamily 1 member A1 (BT)|BTN1A1|BTN

Background: BTN1A1, also named as Butyrophilin subfamily 1 member A1, is a 526 amino acid protein, which contains 1 B30.2/SPRY domain and belongs to the immunoglobulin superfamily. BTN/MOG family. BTN1A1 localizes in the integral component of plasma membrane. BTN1A1 may function in the secretion of milk-fat droplets and may act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. BTN1A1 Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. The calculated molecular weight of BTN1A1 is a 59 kDa, but the modified BTN1A1 protein is about 65-75 kDa.

Molecular Weight: 73 kDa

UniProt: Q13410

Pathways: Activated T Cell Proliferation