STAT6 antibody (pThr645)

Catalog No. ABIN7138872

Product Details anti-STAT6 Antibody

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Binding Specificity: pThr645

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 645 (P-A-T(p)-I-K) derived from Human STAT6.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for STAT6

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Alternative Name: STAT6 (STAT6 Products)

Background:

Background:

Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.

Nelms K, et al. (1999) Annu Rev Immunol. 17:701-738.
Malabarba M G, et al. (1996) Biochem. J. 319:865-872.
Hou J, et al. (1994) Science. 265:1701-1706.
Quelle F W, et al. (1995) Mol Cell Biol. 15: 3336-3343.
Takeda K, et al. (1996) Nature. 380: 627-630.

Aliases: 12S1644 antibody, D12S1644 antibody, IL 4 STAT antibody, IL-4 Stat antibody, IL4 STAT antibody, Interleukin 4 Induced antibody, Interleukin 4 Induced Transcription Factor IL4 STAT antibody, Signal transducer and activator of transcription 6 antibody, Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced antibody, Signal Transducer And Activator Of Transcription 6 Nirs Variant 1 antibody, Signal transducer and activator of transcription 6, interleukin 4 induced antibody, STAT 6 antibody, STAT interleukin4 induced antibody, STAT, interleukin4 induced antibody, Stat6 antibody, STAT6_HUMAN antibody, STAT6B antibody, STAT6C antibody, Transcription factor IL 4 STAT antibody

UniProt: P42226

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response