GRLF1 antibody (pTyr1105)

Catalog No. ABIN7138910

Product Details anti-GRLF1 Antibody

Target: GRLF1 (Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1))

Binding Specificity: pTyr1105

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRLF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Tyrosine 1105(N-I-Y(p)-S-V) derived from Human GRF-1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GRLF1

Target: GRLF1 (Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1))

Alternative Name: ARHGAP35 (GRLF1 Products)

Background:

Background: Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.

Aliases: ARHGAP35 antibody, GAP associated protein p190 antibody, Glucocorticoid receptor DNA binding factor 1 antibody, Glucocorticoid receptor DNA-binding factor 1 antibody, Glucocorticoid receptor repression factor 1 antibody, GRF 1 antibody, GRF-1 antibody, GRF1 antibody, GRLF 1 antibody, GRLF1 antibody, GRLF1_HUMAN antibody, KIAA1722 antibody, MGC10745 antibody, p190 A antibody, p190-A antibody, P190A antibody, P190A, rat, homolog of antibody, p190ARhoGAP antibody, p190RhoGAP antibody, Rho GAP p190A antibody, Rho GTPase-activating protein 35 antibody

UniProt: Q9NRY4

Pathways: Tube Formation