PSMD6 antibody (Regulatory Subunit 6)

Catalog No. ABIN7139704

Product Details anti-PSMD6 Antibody

Target: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Binding Specificity: AA 355-372, Regulatory Subunit 6

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence from Human 26S proteasome non-ATPase regulatory subunit 6 protein (355-372AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PSMD6

Target: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Alternative Name: PSMD6 (PSMD6 Products)

Background:

Background: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

Aliases: 26S proteasome non-ATPase regulatory subunit 6 antibody, 26S proteasome regulatory subunit RPN7 antibody, 26S proteasome regulatory subunit S10 antibody, Breast cancer-associated protein SGA-113M antibody, KIAA0107 antibody, p42A antibody, P44S10 antibody, PFAAP4 antibody, Phosphonoformate immuno-associated protein 4 antibody, Proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 antibody, Proteasome regulatory particle subunit p44S10 antibody, PSMD6 antibody, PSMD6_HUMAN antibody, Rpn7 antibody, S10 antibody, SGA-113M antibody

UniProt: Q15008

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway