PSMD6 antibody (N-Term)

Catalog No. ABIN2779618

There is 1 publication for this product available. The Rabbit Polyclonal anti-PSMD6 antibody is suitable to detect PSMD6 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio) and Guinea Pig. It has been validated for WB.

Quick Overview for PSMD6 antibody (N-Term) (ABIN2779618)

Target: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSMD6 Antibody

Binding Specificity: N-Term

Sequence: PLENLEEEGL PKNPDLRIAQ LRFLLSLPEH RGDAAVRDEL MAAVRDNNMA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PSMD6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 389 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PSMD6 antibody (ABIN2779618)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for PSMD6

Target: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Alternative Name: PSMD6

Background: PSMD6 acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Alias Symbols: KIAA0107, S10, SGA-113M, p44S10, Rpn7
Protein Interaction Partner: UBQLN1, HUWE1, UBC, SUMO2, PSMD14, TP53, SHFM1, PARK2, RNF11, NOS2, PSMD13, PSMD12, PSMD11, PSMD8, PSMD7, PSMD3, PSMD2, PSMD1, PSMC5, PSMC4, PSMC2, PSMD4, PSMC6, PSMC3, PSMC1, PSMB10, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, P
Protein Size: 389

Molecular Weight: 45 kDa

Gene ID: 9861

NCBI Accession: NM_014814, NP_055629

UniProt: Q15008

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway