KCNMB3 antibody (AA 82-207)

Catalog No. ABIN7146342

Product Details anti-KCNMB3 Antibody

Target: KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))

Binding Specificity: AA 82-207

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNMB3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Human Calcium-activated potassium channel subunit beta-3 protein (82-207AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KCNMB3

Target: KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))

Alternative Name: KCNMB3 (KCNMB3 Products)

Background:

Background: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Alters the functional properties of the current expressed by the KCNMA1 channel. Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA. Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations. In contrast, isoform 1 does not induce detectable inactivation of KCNMA1. Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer.

Aliases: BK channel subunit beta 3 antibody, BK channel subunit beta-3 antibody, BKbeta 3 antibody, BKbeta3 antibody, Calcium activated potassium channel beta 3 subunit antibody, Calcium activated potassium channel subfamily M subunit beta 3 antibody, Calcium activated potassium channel subunit beta 3 antibody, Calcium-activated potassium channel antibody, Calcium-activated potassium channel subunit beta-3 antibody, Charybdotoxin receptor subunit beta 3 antibody, Charybdotoxin receptor subunit beta-3 antibody, EG435726 antibody, Gm5707 antibody, Hbeta 3 antibody, Hbeta3 antibody, K(VCA)beta 3 antibody, K(VCA)beta-3 antibody, KCMB3_HUMAN antibody, KCNMB 2 antibody, KCNMB 3 antibody, KCNMB2 antibody, KCNMB3 antibody, KCNMBL antibody, Large conductance voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit antibody, Maxi K channel subunit beta 3 antibody, Maxi K channel subunit beta-3 antibody, Potassium channel, calcium-activated large conductance, subfamily M, beta member 3 antibody, Potassium large conductance calcium activated channel beta 3 subunit antibody, Potassium large conductance calcium activated channel subfamily M beta member 3 antibody, Slo beta 3 antibody, Slo-beta-3 antibody, subfamily M subunit beta-3 antibody

UniProt: Q9NPA1