DCUN1D1 antibody (AA 1-259) (Biotin)

Catalog No. ABIN7149510

Product Details anti-DCUN1D1 Antibody (Biotin)

Target: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Binding Specificity: AA 1-259

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCUN1D1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DCN1-like protein 1 protein (1-259AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DCUN1D1

Target: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Alternative Name: DCUN1D1 (DCUN1D1 Products)

Background:

Background: Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression.

Aliases: DCUN1D1 antibody, DCN1 antibody, DCUN1L1 antibody, RP42 antibody, SCCRODCN1-like protein 1 antibody, DCUN1 domain-containing protein 1 antibody, Defective in cullin neddylation protein 1-like protein 1 antibody, Squamous cell carcinoma-related oncogene antibody

UniProt: Q96GG9