CYP4F11 antibody (AA 38-524)

Catalog No. ABIN7163430

Product Details anti-CYP4F11 Antibody

Target: CYP4F11 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 11 (CYP4F11))

Binding Specificity: AA 38-524

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP4F11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Phylloquinone omega-hydroxylase CYP4F11 protein (38-524AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYP4F11

Target: CYP4F11 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 11 (CYP4F11))

Alternative Name: CYP4F11 (CYP4F11 Products)

Background:

Background: Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine.

Aliases: CYP4F11Cytochrome P450 4F11 antibody, CYPIVF11 antibody, EC 1.14.14.1 antibody, 3-hydroxy fatty acids omega-hydroxylase CYP4F11 antibody, Docosahexaenoic acid omega-hydroxylase antibody, EC 1.14.14.79 antibody, Long-chain fatty acid omega-monooxygenase antibody, EC 1.14.14.80 antibody, Phylloquinone omega-hydroxylase CYP4F11 antibody, EC 1.14.14.78 antibody

UniProt: Q9HBI6

Pathways: Monocarboxylic Acid Catabolic Process